A deer has been spotted running amok through Sydney on Thursday morning, keeping commuters on their toes as the animal rushed through the city.

NSW Police issued a warning most effective diets for quick weight loss city drivers after the deer was spotted near the Anzac Bridge in Pyrmont at about 5.30am. 

'Police are seeking specialist assistance from the RSPCA. Anyone who sees the deer is urged not to approach it and call police,' the release reads.

A NSW Police spokesperson told Daily Mail Australia the deer was still on the loose at 8.15am, with officers at the scene aiding RSPCA officials to capture the deer.

A Taronga Zoo spokesperson told Daily Mail Australia zookeepers were on standby to aid in relocating the deer if they are required.

A Transport Management Centre spokesman told Daily Mail Australia the deer had caused no impact to the road network.

'There have been no road closures or traffic delays from the deer,' they said.

Several listeners contacted

'I couldn't believe what I was seeing. The deer ran out in front of the car it was on Regent st hedging towards the old rail line,' caller Rebecca said.

'There was a guy on a bike next to me and it nearly got him.'

The lost deer comes days after two terrified deer who were spotted rampaging through three Sydney suburbs on October 6. 

The deer were seen prowling down streets across Leichhardt, Balmain and Annandale in the city's inner-west before they were captured by police.

CCTV footage taken in Coleridge Street in Leichhardt showed the two deer walking one behind another in front of a unit block.

One resident said she saw the animals while driving to the gym at 5.30am, while another reported them entering a residential complex about 7.50am.